Encodes a protein that is believed to act as a histidinol-phosphate transaminase involved in histidine biosynthesis. If the gene encoding the other protein shown to have this function, HISN6A (AT5G10330), is disrupted, a residual level of histidine biosynthesis continues, suggesting that HISN6B can somewhat compensate for the loss of HISN6A.
Computational Description
HISTIDINE BIOSYNTHESIS 6B (HISN6B); FUNCTIONS IN: histidinol-phosphate transaminase activity; INVOLVED IN: histidine biosynthetic process; LOCATED IN: chloroplast; CONTAINS InterPro DOMAIN/s: Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Histidinol-phosphate aminotransferase (InterPro:IPR005861), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: histidinol phosphate aminotransferase 1 (TAIR:AT5G10330.2); Has 34816 Blast hits to 34816 proteins in 2921 species: Archae - 1024; Bacteria - 25539; Metazoa - 256; Fungi - 389; Plants - 456; Viruses - 0; Other Eukaryotes - 7152 (source: NCBI BLink).
Encodes a protein that is believed to act as a histidinol-phosphate transaminase involved in histidine biosynthesis. If the gene encoding the other protein shown to have this function, HISN6A (AT5G10330), is disrupted, a residual level of histidine biosynthesis continues, suggesting that HISN6B can somewhat compensate for the loss of HISN6A.
Computational Description
HISTIDINE BIOSYNTHESIS 6B (HISN6B); FUNCTIONS IN: histidinol-phosphate transaminase activity; INVOLVED IN: histidine biosynthetic process; LOCATED IN: chloroplast; CONTAINS InterPro DOMAIN/s: Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Histidinol-phosphate aminotransferase (InterPro:IPR005861), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: histidinol phosphate aminotransferase 1 (TAIR:AT5G10330.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Encodes a protein that is believed to act as a histidinol-phosphate transaminase involved in histidine biosynthesis. If the gene encoding the other protein shown to have this function, HISN6A (AT5G10330), is disrupted, a residual level of histidine biosynthesis continues, suggesting that HISN6B can somewhat compensate for the loss of HISN6A.
Computational Description
HISTIDINE BIOSYNTHESIS 6B (HISN6B); CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferase, class I/classII (InterPro:IPR004839), Histidinol-phosphate aminotransferase (InterPro:IPR005861), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: histidinol phosphate aminotransferase 1 (TAIR:AT5G10330.2); Has 35243 Blast hits to 35243 proteins in 2924 species: Archae - 1037; Bacteria - 25751; Metazoa - 263; Fungi - 377; Plants - 462; Viruses - 0; Other Eukaryotes - 7353 (source: NCBI BLink).