encodes a a novel transcriptional repressor harboring two double-stranded RNA-binding domains and a region homologous to the catalytic domain of RNA polymerase II C-terminal domain phosphatases found in yeast and in animals that regulate gene transcription. Protein exhibits innate phosphatase activity in vitro. Mutants exhibit hyperresponsiveness to ABA, cold, and NaCl.
Computational Description
C-terminal domain phosphatase-like 1 (CPL1); FUNCTIONS IN: double-stranded RNA binding, phosphatase activity, nucleotide phosphatase activity; INVOLVED IN: abscisic acid mediated signaling pathway, negative regulation of transcription, response to abiotic stimulus; LOCATED IN: intracellular; CONTAINS InterPro DOMAIN/s: Double-stranded RNA-binding (InterPro:IPR001159), NLI interacting factor (InterPro:IPR004274); BEST Arabidopsis thaliana protein match is: carboxyl-terminal domain (ctd) phosphatase-like 2 (TAIR:AT5G01270.2); Has 330 Blast hits to 317 proteins in 105 species: Archae - 0; Bacteria - 31; Metazoa - 57; Fungi - 81; Plants - 112; Viruses - 1; Other Eukaryotes - 48 (source: NCBI BLink).
